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Natural Product Research
Formerly Natural Product Letters
Volume 36, 2022 - Issue 8
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Research Articles

A new picrotoxane-type sesquiterpene from Dendrobium nobile Lindl

, , , , , , , & show all
Pages 2112-2117 | Received 01 Sep 2020, Accepted 07 Nov 2020, Published online: 17 Dec 2020
 

Abstract

A picrotoxane-type sesquiterpene, dendroterpene E (1), together with five benzene derivatives (2–6), were isolated from the stems of Dendrobium nobile Lindl. Their structures were elucidated by spectroscopic analysis and X-ray diffraction analysis. Compound 1 was a new picrotoxane-type sesquiterpene with a C-9/C-1/O/C-11 oxetane ring, which was first encountered in this type of compounds. Compounds 1–3 exhibited inhibitory activities against α-glycosidase.

Graphical Abstract

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was supported in part by grants from Hainan Provincial Natural Science Foundation of China (No. 218QN284), Major Technology Project of Hainan Province (No. ZDKJ 201805), Central Public-interest Scientific Institution Basal Research Fund for Chinese Academy of Tropical Agricultural Sciences (No. 1630052016008).

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