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Natural Product Research
Formerly Natural Product Letters
Volume 36, 2022 - Issue 13
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Research Articles

Two new lignans from Zanthoxylum armatum

Yan Suna College of Pharmaceutical Sciences, Southwest University, Chongqing, P.R. ChinaView further author information
,
Qing-Hong Zenga College of Pharmaceutical Sciences, Southwest University, Chongqing, P.R. ChinaView further author information
,
Hui-Qiang Lua College of Pharmaceutical Sciences, Southwest University, Chongqing, P.R. China;b Center for Drug Screening and Research, School of Geography and Environmental Engineering, Gannan Normal University, GanzhouJiangxi, P.R. ChinaView further author information
,
Fan-Cheng Menga College of Pharmaceutical Sciences, Southwest University, Chongqing, P.R. ChinaView further author information
,
Yong Shena College of Pharmaceutical Sciences, Southwest University, Chongqing, P.R. ChinaView further author information
,
Wei-You Zengc Agricultural Technology Extension Center of Jiangjin District, Chongqing, P.R. ChinaView further author information
,
Hao Chic Agricultural Technology Extension Center of Jiangjin District, Chongqing, P.R. ChinaView further author information
,
Yu-Qiang Zhouc Agricultural Technology Extension Center of Jiangjin District, Chongqing, P.R. ChinaView further author information
&
Min Chena College of Pharmaceutical Sciences, Southwest University, Chongqing, P.R. ChinaCorrespondence[email protected]
View further author information
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Pages 3331-3336 | Received 06 Oct 2020, Accepted 22 Nov 2020, Published online: 08 Dec 2020
 
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Abstract

Zanthoxylum armatum, its peels possessed better special flavour, as well as various bioactivities, such as anti-inflammatory, anti-microbial and anti-tumour. In our chemical investigation on the peels of Z. armatum, two new lignans (1 and 2) and three known lignans (3–5) were isolated by silica gel column chromatography, ODS column and preparative HPLC and their structures were established as zanthlignans A and B (1–2), (-)-asarinin (3), phylligenin (4) and planispine A (5) through various spectroscopic techniques including UV, IR, HR-ESI-MS, NMR and CD methods.

Graphical Abstract

Disclosure statement

The author declares that there is no conflict of interest.

Additional information

Funding

This work was supported by National Modern Agricultural Industrial Park Construction Subproject (No. BA202000331) and Chongqing Social Undertaking and Livelihood Security Project (No. cstc2017shmsA130079).

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