A new quinic acid derivative with α-glucosidase inhibitory activity from the fruit of Gardenia jasminoides J.Ellis

Abstract

A new quinic acid derivative (1) along with seven known compounds (2–8) were isolated from the fruit of Gardenia jasminoides J.Ellis. All the structures of the isolated compounds were elucidated on the basis of the analysis of multiple spectroscopic data. The α-glucosidase inhibitory effects of the isolated compounds were investigated. The results showed that compounds 1–3, 6, and 8 have moderate α-glucosidase inhibitory activities.

Graphical Abstract

Keywords:

• Rubiaceae
• Gardenia jasminoides J.Ellis
• quinic acid
• α-glucosidase inhibitory effect

Disclosure statement

The authors have declared that there is no conflict of interest.

Additional information

Funding

This work was supported by the Central Government Guide Local Science and Technology Development Funds ([2016]149), Science and Technology Key Project of Henan Province (182102410080), Henan Province High-level Personnel Special Support (ZYQR201810080), and National Natural Science Foundation of China (NO. 82003946).