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Natural Product Research
Formerly Natural Product Letters
Volume 37, 2023 - Issue 7
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Short Communications

Two new sesquiterpenes from Xylopia vielana

Ling ChenFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, P. R. ChinaView further author information
,
Ping YangFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, P. R. ChinaView further author information
,
Mi ZhangFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, P. R. ChinaORCID Iconhttps://orcid.org/0000-0001-6410-6128View further author information
ORCID Icon &
Weifeng DaiFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, P. R. ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-1148-5907View further author information
ORCID Icon
Pages 1199-1204 | Received 06 May 2021, Accepted 17 Sep 2021, Published online: 29 Sep 2021
 
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Abstract

Two new sesquiterpenes (1–2) and six known analogues (3–8) were isolated from the branches and leaves of Xylopia vielana Pierre. The structures of the new compounds were identified by analyzing 1 D and 2 D NMR data and HRESIMS data, combined with induced and calculated circular dichroism experiments. In addition, compounds 1–4, 7 and 8 showed notable nitric oxide (NO) inhibitory effects (IC50 < 10 μM) on the model of the lipopolysaccharide (LPS)-activated RAW 264.7 macrophages.

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Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was supported by National Natural Science Foundation of China (No. 32060105) and Personnel Training Project of Yunnan, China (KKSY201626035).

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