Abstract
Two new phloroglucinols, acronyols A (1) and B (2) along with the four known (3–6) pholoroglucinols were identified following anti-inflammatory activity guided fractionation from the fruits of Acronychia crassipetala (family Rutaceae). The pholoroglucinols (1–6) were evaluated for their inhibitory effects on NO production and downregulation of TNF-α in RAW 264.7 macrophage cell lines.
Graphical Abstract
Acknowledgements
The authors would like to acknowledge Dr. Scott Willis (Biomedical Magnetic Resonance Facility Manager, Western Sydney University) for providing his technical expertise in the NMR experiments performed. We also would like to acknowledge the Mass Spectrometry Facility (MFS) of Western Sydney University for access to its instrumentation and grateful for the assistance of Mr Meena Mikhael.
Disclosure statement
No potential conflict of interest was reported by the authors.