Abstract
A new xanthone glycoside, 1,8-dihydroxyl-2,5-dimethoxy-xanthone-6-O-β-D-glucoside (1), along with two known xanthone glycosides and two flavonoid glycosides were isolated from the aerial parts of Lomatogonium rotatum (L.) Fries es Nym. The structure of 1 was elucidated by analysis of its spectroscopic data, including UV, IR, HR-ESI-MS and extensive 1 D and 2 D NMR techniques. In vitro test, compound 1 behaved similarity to swertianolin against α‑glucosidase and more potent inhibitory effects than the positive control, acarbose.
Graphical Abstract
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Acknowledgements
This work was supported by the National Key R&D Program of China (2019YFC1712300), open fund project of Key Laboratory of Mongolian Medicine R & D project of Ministry of Education (MDK2020022) and Inner Mongolia Autonomous Region Natural Science (2021MS08070). Foundation in China.
Disclosure statement
No potential conflict of interest was reported by the author(s).