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Natural Product Research
Formerly Natural Product Letters
Volume 38, 2024 - Issue 1
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Research Articles

Two new anthraquinone derivatives from Saprosma crassipes H. S. Lo

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Pages 91-96 | Received 20 Apr 2022, Accepted 18 Jul 2022, Published online: 03 Aug 2022
 

Abstract

Two new anthraquinone derivatives sapranquinones A and B (1 and 2) together with two known biogenetically related anthraquinone derivatives (3 and 4) were isolated from the stems of Saprosma crassipes H. S. Lo. The structures of these compounds were elucidated using comprehensive spectroscopic methods. Compounds 1-4 were evaluated for their antibacterial activities and compounds 1 and 3 had a broad spectrum antibacterial activity against Staphylococcus albus, Escherichia coli, Bacillus cereus, Micrococcus tetragenus, and Micrococcus luteus with MIC values ranging from 1.25 to 5 μg/mL.

Graphical Abstract

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was supported by the Hainan Province Natural Science Foundation (220QN252 and 2019RC174) and the Innovative Research Team Project of Ministry (IRT-16R19).

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