https://orcid.org/0000-0001-8615-4710
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Abstract
Three new coumarin derivatives named maytenucoums A-C (1-3), along with six known analogs (4-9), were isolated from the branches of Maytenus hookeri. Their structures were determined by comprehensive spectroscopic data analysis, including NMR and HR-ESIMS. In the preliminary assays, compound 4 showed cytotoxic activity against the A549, SK-Hep1 and HCT116 cells with IC50 values of 29.0, 28.6 and 54.4 μM, respectively.
GRAPHICAL ABSTRACT
Disclosure statement
No potential conflict of interest was reported by the authors.
Additional information
Funding
This work was supported by Science & Technology Plan of Zunyi [ZSKHHZ(2020)66], Guizhou; Provincail Science and Technology support program(QKHZC-2020-4Y156), the Science and Technology Foundation of Guizhou Province (QKHJC-ZK[2021]YB513), New Seedling Cultivation and Innovation Exploration of Zunyi Medical University ([2017]5733–059), Zunyi Medical University Doctoral Research Funding Project (F-988), the Xin Miao Funding of Zunyi Medical University（QKPTRC[2020]-003, QKPTRC[2019]-005）.