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Natural Product Research
Formerly Natural Product Letters
Volume 38, 2024 - Issue 5
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Research Articles

Chemical composition and biological activities of Lonicera caprifolium L. (Caprifoliaceae) essential oil

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Pages 719-726 | Received 12 Dec 2022, Accepted 16 Mar 2023, Published online: 24 Mar 2023
 

Abstract

This work aimed to investigate the chemical composition, antioxidant activity, antinociceptive effect, and wound healing activity of the Lonicera caprifolium L. flower essential oil (LCEO). Linalool (16.42%), d-limonene (9.99%), and α-cadinol (10.65%) were the most prevalent components of the LCEO. The LCEO revealed moderate DPPH and ABTS radical-scavenging activity. LCEO exhibited potent antinociceptive activity in acetic acid-induced writhing and hot plate-induced pain model; LCEO reduced 73.88 ± 2.78% of writhing and significantly increased pain withdrawal latency in the mice, respectively. The LCEO also presented a potent wound healing effect, with 98.08 ± 1.37% wound closure on the 12th day of treatment. The results of the study demonstrate antioxidant and wound healing potential with antinociceptive effect. To the best of our knowledge, this is the first report on the bioactivities of L. caprifolium L. essential oil.

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Disclosure statement

No potential conflict of interest was reported by the authors.

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Funding

The author(s) reported there is no funding associated with the work featured in this article.

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