Investigation of Fetuin-A pathway in diabetes mellitus formation in rats exposed to elf magnetic fields

ABSTRACT

The presence of technological devices in our lives has increased exposure to environmental electromagnetic fields. As a result of this, especially Cancer and Diabetes are increasing.Rats were divided into 3 groups with 12 rats in each group. The 1st experimental group (n = 12) was exposed to a 50 Hz ELF magnetic field of 0.4 mT for 6 hours a day for 5 days, the 2nd experimental group (n = 12) was exposed for 10 days, and the control group (n = 12) was never exposed to a magnetic field. After completing the applications, blood collection from the rats was performed under appropriate conditions, measurements were made in the laboratory, and statistical analysis was performed between the groups. There was no significant difference between the groups in the results of transaminases and lipid profiles and C-Peptide. There was no significant difference in insulin, urea, creatinine, Na, K, Ca, and uric acid parameters between the groups. However, there was a significant increase in glucose, HbA1c, and Hba1 IFCC values between the control group and the experimental groups (p < .001). There was a significant increase in the level of Fetuin-A between the control group and the experimental groups (p < .05). There was an increase in the Fetuin-A, Glucose, HbA1c, and Hba1c IFCC values in both of the experimental groups compared to the control group. We believe that an increase in these values may cause Type 3 diabetes.

KEYWORDS:

• Magnetic field
• diabetes mellitus
• Fetuin-A
• insulin
• HbA1c
• blood glucose

Acknowledgments

It was approved by the Harran University Animal Experiments Local Ethics Committee with the decision dated 29/04/2019 and numbered 01-02 and was supported by the Harran University Scientific Research Projects Unit (HÜBAP) with the project number 19285.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

This scientific study was supported by the at Harran University Scientific Research Projects Unit (HÜBAP) with the Project Number 19285.