Compressive mechanical properties of hierarchical porous bioactivity PEEK gradient materials

Abstract

Based on the original bone structure and components, medical PEEK modified by adding multi-doped nano hydroxyapatite and calcium carbonate whiskers to match the mechanical properties of the original bone compositions, and adapted microcellular foam process to obtain the hierarchical porous functionally graded structure. The addition of adsorbent-active cross-linking agents, such as Type I collagen, osteo-inductive fluid, and active enzymes were used to improve the hydrophobicity of the medical PEEK material surface. The multi-constituent elements and gradient pore structure similar to the original bone were easier to activate the modified material surface, produce cell adsorption and promote cell growth and differentiation.

KEYWORDS: :

• Hierarchical porous structure
• Medical PEEK composites
• biocompatibility
• compression performance
• biomechanics

Disclosure Statement

The authors declare that they have no conflicts of interest.

Additional information

Funding

The project is supported by Natural Science Foundation of Zhejiang Province of China (Grant No. LY22E050001); State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Science (LSL-2113), Major/Key research plan of the Jinhua Science and Technology Agency (2021-1-075), Application research items of public welfare technology of Jinhua Science and Technology Agency (2023), and National innovation and entrepreneurship training program for college students (202213276005 and 202013276004).