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Molecular Crystals and Liquid Crystals Volume 693, 2019 - Issue 1: Proceedings of 15th International Conference on Frontiers of Polymers and Advanced Materials, Penang, Malaysia, June 17 - 21, 2019, Part-1
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Articles

T-jump and circular dichroism: folding dynamics in proteins and DNA

Pascale ChangenetLaboratoire d’Optique et Biosciences, Ecole Polytechnique, CNRS, INSERM, IP Paris, Palaiseau Cedex, FranceView further author information
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François HacheLaboratoire d’Optique et Biosciences, Ecole Polytechnique, CNRS, INSERM, IP Paris, Palaiseau Cedex, FranceCorrespondence[email protected]
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Pages 49-56 | Published online: 02 May 2020
 
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Abstract

We review recent experimental work combining circular dichroism spectroscopy and T-jump experiment to investigate elementary dynamics in the folding/unfolding of biomolecules. A nanosecond set-up is presented for poly(Glutamic acid) studies whereas a millisecond one is developed for investigation of DNA G-quadruplex dynamics.

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Funding

The LABEX PALM (QUADfold and OSPEG projects, ANR-10-LABX-0039-PALM) is gratefully acknowledged for financial support.

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