REDD-PAC Cohort Description: Researching Dual Diagnosis – Prognosis and Characteristics

Abstract

Objective

Evidence from real-world integrated dual diagnosis treatment programs is limited. In 2017 we decided to establish the REDD-PAC cohort with the aim to provide more in-depth information regarding the effect of integrated treatment.

Methods

The REDD-PAC cohort includes more than 2,500 patients with dual diagnosis that have been treated at an in-patient department specializing in the integrated treatment of both psychiatric illness and substance use disorder in Denmark in the period from 2002 to 2017. The collected data included information on diagnosis as well as patient-completed questionnaires regarding anxiety, depression, self-worth, and use of substances. Data regarding medications prescribed and administered, weight, height, and blood pressure were also included.

Results

The primary diagnosis was psychosis spectrum disorder (37.0%), followed by affective disorders (18.8%). More than two-thirds of the patients were male, and most patients had a weak connection to the labor market and basic schooling. Patients were generally very motivated for treatment.

Conclusions

Further linking the data to Danish national register data makes it possible to follow individual trajectories pre- and post-admission as well as to access complete follow-up data regarding long-term outcomes, e.g., use of health services, mortality, morbidity, crime, and social circumstances. This article describes both the overarching aims of the REDD-PAC cohort and the basic diagnostic and sociodemographic characteristics of the cohort.

Keywords:

• Dual diagnosis
• cohort profile
• epidemiology
• substance use disorder
• psychiatry
• Denmark
• co-morbidity

Correction Statement

This article has been corrected with minor changes. These changes do not impact the academic content of the article.

Disclosure statement

Drs. Solvej Mårtensson, Katrine Johansen, and Jakob Krarup report no financial relationships with commercial interests. Dr. Signe Düring reports having been a speaker at conferences and Lundbeck Pharmaceuticals teaching sessions and received a salary for speaking on subjects not related to pharmaceutical treatment or products.

Data availability statement

The group welcomes contact from potential collaborators. Information regarding the cohort can be obtained by contacting the Competence Center for Dual Diagnosis. Please email corresponding author ([email protected]).

Additional information

Funding

The cohort is funded by the Research Committee, Psychiatric Center Sct. Hans, the Muusfeldt Foundation [Grant number 2017-871] and Helsefonden [Grant number 19-A-0042].