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CASE REPORT

Congenital Pouch Colon: Further Histopathological Perspectives

, , &
Pages 881-888 | Received 16 Aug 2021, Accepted 19 Oct 2021, Published online: 12 Nov 2021
 

Abstract

Background:

Congenital pouch colon is an uncommon anomaly worldwide and is usually associated with anorectal malformations. Imperforate anus with a large air fluid level on the abdominal x ray suggests the diagnosis. Most cases are diagnosed in neonates and an early management limit complications. Few studies have documented the histopathological features of congenital pouch colon.

Case report:

We present two cases with varied associated anomalies (Case 1 with rectovesical fistula, Case 2 with Mayer Rokitansky Kuster Hauser syndrome) and their histopathological features. Immunohistochemistry for calretinin showed paucity of ganglion cells and intrinsic fibers with occasional punctate positivity. The c-Kit immunostain documented fewer interstitial cells of Cajal. Cystitis glandularis with intestinal metaplasia (Case 1) and an additional muscle layer (Case 2) are described.

Discussion/Conclusion:

These novel histopathological features characterize the entity further and may be related to genesis of the pouch and its clinical manifestations.

Disclosure statement

The author(s) declare no potential conflicts of interest.

Funding

This research received no specific grant from any funding agency in public, commercial or not-for-profit sector.

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