Neural coding of human values is underpinned by brain areas representing the core self in the cortical midline region

ABSTRACT

The impact of human values on our choices depends on their nature. Self-Transcendence values motivate us to act for the benefit of others and care for the environment. Self-Enhancement values motivate us to act for our benefit. The present study examines differences in the neural processes underlying these two value domains. Extending our previous research, we used fMRI to explore first of all neural correlates of Self-Transcendence vs Self-Enhancement values, with a particular focus on the putative role of the medial prefrontal cortex (MPFC), which has been linked to a self-transcendent mind-set. Additionally, we investigated the neural basis of Openness to Change vs Conservation values. We asked participants to reflect on and rate values as guiding principles in their lives while undergoing fMRI. Mental processing of Self-Transcendence values was associated with higher brain activity in the dorsomedial (BA9, BA8) and ventromedial (BA10) prefrontal cortices, as compared to Self-Enhancement values. The former involved activation and the latter deactivation of those regions. We did not detect differences in brain activation between Openness to Change vs Conservation values. Self-Transcendence values thus shared brain regions with social processes that have previously been linked to a self-transcendent mind-set, and the “core self” representation.

KEYWORDS:

• Basic human values/Schwartz’s value model
• self-transcendence
• self-enhancement
• fMRI

Acknowledgments

We thank Armin Heinecke from BrainVoyager for helping with optimization of fMRI data analyses. This study was supported by the National Centre for Mental Health at Cardiff University. NCMH is funded by the National Institute for Social Care and Health Research, Welsh Government, Wales (Grant No. BR09).

Disclosure statement

No potential conflict of interest was reported by the author(s).

Supplementary material

Supplemental data for this article can be accessed here.

Additional information

Funding

This work was supported by the National Centre for Mental Health (NCMH) at Cardiff University. NCMH is funded by the National Institute for Social Care and Health Research (NISCHR), Welsh Government, Wales [Grant No. BR09].