Organotin compounds in seafood by ultrasonic assisted extraction and gas chromatography-triple quadrupole tandem mass spectrometry

ABSTRACT

Although restricting environmental quality values for organotin compounds (OTs) are set by Directive 2013/39/EU of the European Parliament, marine environment remains being affected due to maritime circulation at global scale. Fish and seafood accumulate OTs, making fish and seafood consumption the main source of OTs in humans. Because of the fish and seafood matrices complexity and the required low limits of detection, a robust and fast procedure for the quantification of OTs in fish and seafood, using ultrasound-assisted extraction and gas chromatography–tandem mass spectrometry, was validated and applied. Detection (2.7 µg Sn kg⁻¹) and quantification (8.0 µg Sn kg⁻¹) limits, repeatability and intermediate precision (<10%), accuracy by analysing ERM®-CE477 Mussel Tissue and analytical recoveries (65–122%) were assessed. Multivariate analysis shown that the matrix effect for some OTs displayed good negative correlation with the fat and protein content. Health risk assessment of OTs intake revealed no serious risk for human consumption.

KEYWORDS:

• Emerging pollutants
• food safety
• organotin compounds
• gas chromatography-triple quadrupole tandem mass spectrometry

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

Financial support by the Program of Consolidation and Structuring of Units of Competitive Investigation of the University System of Galicia (Xunta de Galicia) (reference: ED431C 2021/56) potentially co-financed by ERDF, and by the Ministry of Economy and Competitiveness (ARPA-ACUA, project reference: CTM2016-77945-C3-3-R). Funding for open access charge: Universidade da Coruña/CISUG.