Occurrence and risk assessment of sterigmatocystin in agricultural products and processed foods in Korea

ABSTRACT

Sterigmatocystin (STC), a carcinogenic mycotoxin, is known to be produced during the biosynthetic pathway of aflatoxin B₁. STC in various foods was determined by LC-MS/MS and its risks were assessed. The analytical method was validated in different food categories, and the performance was acceptable based on the criteria of AOAC. A total 1,135 samples (613 agricultural products and 522 processed foods) were analysed, and STC was detected in 46 samples, indicating a detection rate of 4.1%. STC was found in the range of 0.08–10.07 ng/g, and the detection rates of STC were 3.9% in agricultural products and 4.2% in processed foods. The exposure to STC by average consumption of foods was estimated to 0.09 ng/kg b.w./day. The margin of exposure (MOE) approach was applied to assess the risk of STC, and MOE for the whole population was over 1 × 10⁶. Exposure to STC from the consumption of foods distributed in Korea is unlikely to cause human health problems.

KEYWORDS:

• Contamination
• monitoring
• mycotoxins
• risk assessment
• sterigmatocystin

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

This study was supported by a grant [19161MFDS022] from the Ministry of Food and Drug Safety in 2019.