Moderate intensity endurance exercise on responses of relative cardiovascular parameters of primary and secondary hypertensive patients: protocol for a randomised controlled trials

Abstract

Background

Physical activity has been recommended for the prevention and complementary treatment of hypertension. The objective of this research is to compare the responses of relative cardiovascular parameters of primary and secondary hypertensive patients to moderate-intensity aerobic exercise.

Methods

One hundred participants are expected to be recruited and randomised into four groups, namely, the Primary Hypertension, and Secondary Hypertension Experimental groups, primary Hypertension and Secondary Hypertension Control groups. The participants in the experimental groups will undergo cycle-ergometer training, 3 per week, for 30 minutes, while the control groups will be non-exercise control. Participants’ blood pressure will be measured using a calibrated digital monitor, heart rate (HR) will be measured using a fingertip digital pulse oximeter, and rate pressure product (RPP) will be calculated by multiplying systolic BP and HR at baseline and the end of 6weeks. Data will be analysed using descriptive and inferential statistics, multivariate analysis for between the groups and paired t-test within the group. Alpha will be set at 0.05.

Results

Though different additional strategies such as exercise and lifestyle modifications exist for the control of hypertension. But no strategies have been identified to compare the cardiovascular responses of primary and secondary hypertensive patients to moderate-intensity aerobic exercise.

Keywords:

• Primary and secondary hypertension
• cardiovascular parameters
• moderate intensity aerobic exercise
• cardiovascular endurance
• complementary therapy

Acknowledgements

The authors would like to thank the study patients. The experiments comply with the current Nigeria laws.

Availability of data and materials

Relevant files of this work will be shared on request.

Ethics approval and consent to participate

All the patients will sign an informed consent form before their participation in the study to conform with the Helsinki declaration standards.

Disclosure statement

The authors report no declarations of interest.