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Epigenomics Volume 12, 2020 - Issue 8
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Research Article

RNA-Seq profiling of circular RNAs in human small cell lung cancer

Chenxi Zhang1 Central Laboratory, Nanjing Chest Hospital, Medical School of Southeast University, Nanjing, PR China;2 Central Laboratory, Nanjing Brain Hospital, Nanjing Medical University, Nanjing, PR ChinaORCID Iconhttps://orcid.org/0000-0001-6560-177X
ORCID Icon,
Bin Zhang1 Central Laboratory, Nanjing Chest Hospital, Medical School of Southeast University, Nanjing, PR China;2 Central Laboratory, Nanjing Brain Hospital, Nanjing Medical University, Nanjing, PR China
,
Baiyin Yuan3 Biomedical Research Institute, College of Life Science and Health, Wuhan University of Science and Technology, Wuhan, PR China
,
Caiping Chen4 Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, PR China
,
Ying Zhou1 Central Laboratory, Nanjing Chest Hospital, Medical School of Southeast University, Nanjing, PR China;2 Central Laboratory, Nanjing Brain Hospital, Nanjing Medical University, Nanjing, PR China
,
Yu Zhang5 Department of Respiratory Medicine, Nanjing Chest Hospital, Medical School of Southeast University, Nanjing, PR China;6 Department of Respiratory Medicine, Nanjing Brain Hospital, Nanjing Medical University, Nanjing, PR China
,
Zhihong Sheng1 Central Laboratory, Nanjing Chest Hospital, Medical School of Southeast University, Nanjing, PR China;2 Central Laboratory, Nanjing Brain Hospital, Nanjing Medical University, Nanjing, PR China
,
Nan Sun1 Central Laboratory, Nanjing Chest Hospital, Medical School of Southeast University, Nanjing, PR China;2 Central Laboratory, Nanjing Brain Hospital, Nanjing Medical University, Nanjing, PR China
&
Xiaoyuan Wu1 Central Laboratory, Nanjing Chest Hospital, Medical School of Southeast University, Nanjing, PR China;2 Central Laboratory, Nanjing Brain Hospital, Nanjing Medical University, Nanjing, PR ChinaCorrespondence[email protected]
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Pages 685-700 | Received 12 Dec 2019, Accepted 03 Feb 2020, Published online: 21 Feb 2020
 
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Abstract

Aim: We aimed to explore the circular RNA (circRNA) profile of small-cell lung cancer elopment of targeted therapies for SCLC.

Supplementary data

To view the supplementary data that accompany this paper please visit the journal website at: www.tandfonline.com/doi/suppl/10.2217/epi-2019-0382

Financial & competing interests disclosure

This work was supported by National Natural Science Foundation of China (grant number 81802820) to C Zhang. This work was also partially supported by the Youth Science and Technology Backbone Training Program of Nanjing Brain Hospital. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

No writing assistance was utilized in the production of this manuscript.

Ethical conduct of research

All of the tissue specimens for this study were obtained with informed patient consent from the Nanjing Chest Hospital Biobank. The study was conducted in accordance with the Declaration of Helsinki, and the research protocol was reviewed and approved by the Medical Ethics Commission of Nanjing Chest Hospital.

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