https://orcid.org/0000-0001-8843-082X
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Abstract
Pharmacogenomics is considered to be the low-hanging fruit in the tree of genomic medicine with numerous examples of its successful implementation in the clinic. In this perspective, we provide details about the potential clinical application of pharmacogenomics in African populations by using relevant drug cases and high-throughput genomics approaches; involving numerous countries and stakeholders; and most importantly exploiting the existing knowledge of respective large-scale initiatives. We emphasize on the necessity of constructing appropriate frameworks for government policies in African countries. We also provide input about different initiatives in the field of genomics medicine implementation in Africa, not only for their potential for synergy and collaboration among them, but also as models for replication in other regions worldwide, aiming for healthcare improvement.
Acknowledgments
This article is the outcome of an essay prepared within the scope of the evaluation of B Mathuba for the module ‘Pharmacogenomics in clinical care and drug discovery’ of the Golden Helix Academy (www.academy.goldenhelix.org). GP Patrinos is full member and national representative of the European medicines Agency, CHMP-Pharmacogenomics Working Party (Amsterdam, the Netherlands).
Financial & competing interests disclosure
The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.
No writing assistance was utilized in the production of this manuscript.