Abstract
Aim: Carpal tunnel syndrome (CTS) is a very common entrapment neuropathy characterized by pain and paresthesia in the territory of the median nerve. Although this syndrome has a considerable impact on the patient’s quality of life, its medical treatment is far from optimal. Material & methods: We performed an observational study to evaluate Nucleo CMP ForteTM in patients with electromyography-confirmed, mild–moderate CTS. Pain was assessed using a visual analog scale, electromyogram and the SF-36. Results: Pain decreased significantly after 6 months. Quality of life improved significantly in the pain dimensions. No significant differences were observed in electromyographic findings. No adverse events were reported. Conclusions: Nucleotides could prove useful for the nonsurgical treatment of CTS. Further studies are necessary to confirm this.
Acknowledgements
The authors are grateful to P Roset for his contribution to the editing of the paper.
Author contributions
J Montero participated in the study design and interpretation of data. Y Martínez participated in the acquisition and interpretation of data. A Tejado participated in the acquisition and interpretation of data. P Arroyo participated in the acquisition, analysis and interpretation of data. M Povedano participated in the study design and interpretation of data. C Tebe participated in the analysis and interpretation of data. JL Lorenzo participated in the interpretation of data and in the edition of the manuscript. All of the authors participated in drafting the manuscript or revising it critically. All of the authors approve the final approval of the version to be published.
Financial & competing interests disclosure
JL Lorenzo is a Ferrer employee. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
Medical writing support was provided by Content Ed Net (Madrid, Spain) and was funded by Ferrer.
Ethical conduct of research
The study was approved by the Ethics Committee of our hospital and was performed in accordance with the International Conference on Harmonization Good Clinical Practice guidelines and the Declaration of Helsinki. The authors state that they have obtained written informed consent from the patient/patients for the inclusion of their medical and treatment history within this case report.