Sexually Transmitted Infection Control with Sex Workers: Regular Screening and Presumptive Treatment Augment Efforts to Reduce Risk and Vulnerability

Figures & data

Table 1 Prevalence of sexually transmitted infections in female sex worker populations

Figure 1 A model of targeted interventions for interrupting transmission dynamics in commercial sex settings

Figure 2 Estimated new HIV infections over one year in two scenarios

Table 2 Select antibiotic treatment regimens used for presumptive treatment (PT) of sex workers

PT regimen	Issues
1. Azithromycin 1 G orally as a single dose	May not be optimal dose for gonorrhoea leading to development of resistance (theoretical)
2. Azithromycin 2 G orally as a single dose	Better coverage of gonorrhoea but high incidence of gastrointestinal side effects
3. Azithromycin 1 G orally as a single dose plus Cefixime 400 mg orally as a single dose Possible substitutes: Ceftriaxone 125–250 mg IM or a quinolone for gonorrhoea coverage Doxycycline 100 mg orally twice daily for 7 days for chlamydia coverage	Better coverage of gonorrhoea with fewer side effects and lower cost than option 2 Ceftriaxone requires injection. Quinolone resistance widespread in some areas Doxycycline 7-day treatment raises problems of poor adherence and incomplete cure