Cellular immune response in prognosis of Bell's palsy and its relation to clinical and electrophysiological findings

Peer review under responsibility of Alexandria University Faculty of Medicine

Available online 29 March 2012

Figures & data

Figure 1 Compound muscle action potential recorded from (a) frontalis, (b) orbicularis occuli, (c) nasalis (d) orbicularis oris muscles of patient's healthy (upper 2 traces) and affected sides (lower 2 traces).

Table 1 Comparison of the electroneurography of the facial muscles between patients and controls.

Parameter	Patients mean ± SD	Control mean ± SD	t	p	Cut off values
Electroneurography:
Frontalis	45.6 ± 30.4	73.7 ± 23.6	−2.524	0.02^*	26.5
Orbicularis occuli	51.1 ± 34.2	72.6 ± 16.6	−1.975	0.066	41.4
Nasalis	49.3 ± 27.8	85.9 ± 10.8	−4.307	0.001^*	64.3
Orbicularis oris	47.3 ± 30.6	83 ± 11.3	−3.602	0.003^*	60.4

* Significant if p ⩽ 0.05.

Table 2 Comparison of initial and follow up values of House and Brackmann grading system, affected facial nerve CMAP latency and amplitude, electroneurography and blink reflex responses among patients.

	Initial mean ± SD (n = 20)	Follow up mean ± SD (n = 20)	T	P
House and Brackmann	4.5 ± 1.5	1.7 ± 1.4	4.66	0.001^*
Facial nerve CMAP latency (ms):
Frontalis	3.3 ± 0.9	3.3 ± 0.6	−0.4	0.69
Orbicularis occuli	3.4 ± 0.7	3.3 ± 0.7	−0.6 (Z)	0.60
Nasalis	3.0 ± 0.6	3.0 ± 0.3	−1.0	0.43
Orbicularis oris	2.6 ± 0.8	3.3 ± 0.9	−2.0	0.13
Facial nerve CMAP amplitude (mV):
Frontalis	0.3 ± 0.3	0.7 ± 0.4	−2.0	0.10
Orbicularis occuli	0.7 ± 0.6	0.8 ± 0.6	−0.0	1.00
Nasalis	1.0 ± 0.7	1.3 ± 1.0	−0.7	0.49
Orbicularis oris	2.6 ± 2.4	2.6 ± 2.3	−0.7 (Z)	0.52
Electroneurography:
Frontalis	45.6 ± 30.4	67.5 ± 39.7	−1.2	0.28
Orbicularis occuli	51.1 ± 34.2	60.8 ± 43.5	0.8	0.48
Nasalis	49.3 ± 27.8	53.8 ± 35.0	0.9	0.39
Orbicularis oris	47.3 ± 30.6	59.4 ± 39.6	0.6	0.56
Blink reflex:
R1	11.6 ± 0.5	10.1 ± 0.8	6.0	0.10
Ipsilateral R2	29.6 ± 3.6	31.3 ± 4.3	11.0	0.06^*
Contralateral R2	31.4 ± 3.8	31.6 ± 3.4	4.7	0.13

* Significant if p ⩽ 0.05. Z: Wilcoxon test was used.

Table 3 Comparison of peripheral blood mononuclear cell subsets between patients and control groups.

	Patients (n = 20) Mean ± SD	Controls (n = 15) Mean ± SD	t	P
CD3+	62.4 ± 15.3	80.5 ± 7.7	−4.1(Z)	0.001^*
CD4+	40.7 ± 6.2	47.9 ± 9.7	−2.1	0.050^*
CD8+	21.7 ± 3.4	24.5 ± 2.5	−2.4	0.023^*
CD19+	8.3 ± 5.6	7.5 ± 4.5	0.4(Z)	0.69

* Significant if p ⩽ 0.05. Z: Mann–Whitney statistics was used.