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Arab Journal of Urology
An International Journal
Volume 10, 2012 - Issue 4
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Uroscience

Protection against renal ischaemia/reperfusion injury: A comparative experimental study of the effect of ischaemic preconditioning vs. postconditioning

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Pages 418-424 | Received 22 Jun 2012, Accepted 15 Aug 2012, Published online: 05 Apr 2019

Figures & data

Table 1 The effect of Ipre and Ipost on the variables of renal function, from 10 rats at each sample time.

Table 2 The effect of Ipre and Ipost on lipid peroxidation products (MDA), and the antioxidants SOD and GSH.

Figure 1 The effects of Ipre and Ipost on the tubulo-interstitial damage score at 2, 24 and 48 h after ischaemia in the different groups. Significant difference from the sham group, #control group, and $significant from the Ipre group. One-way anova with Scheffe’s posthoc test (P < 0.05).

Figure 2 Sections of the kidney from the sham group (A), showing a normal appearance of glomeruli and tubules (score 0), and the control group (B), showing tubular necrosis at OSOM in >50% of tubules, score 4. H&E ×400).

Figure 3 Sections from kidneys of the Ipre group at 24 h (A), showing tubular necrosis at OSOM in ≈35% of tubules, score 3 (H&E ×400); and the Ipre group at 48 h (B) showing tubular necrosis at OSOM in >10% of tubules, score 2 (H&E ×400).

Figure 4 Sections from kidneys of the Ipost group at 24 h (A), showing tubular necrosis at OSOM in ≈70% of tubules, score 4 (H&E ×400), and in the Ipost group at 48 h (B) showing tubular necrosis at OSOM in ≈60% of tubules, score 4 (H&E ×400).