Geographical differences in semen characteristics of 13 892 infertile men

Peer review under responsibility of Arab Association of Urology.

Figures & data

Table 1 Sperm analysis of infertile men: the MENA region compared to non-MENA (n = 13,892).

Variable, mean (SE)	MENA n = 8799	Non-MENA n = 5093	P
Age, years	35.06 (0.09)	36.73 (0.11)	<0.001
Volume, mL	3.15 (0.02)	2.97 (0.03)	<0.001
Count, × 10^6 sperm/mL	29.77 (0.30)	36.85 (0.43)	<0.001
Total motility, %	44.96 (0.26)	47.30 (0.33)	<0.001
PMot, %	24.60 (0.25)	25.73 (0.33)	<0.001
ABF, %	80.73 (0.25)	78.54 (0.33)	<0.001
SDF, ^* %	26.65 (0.69)	27.94 (0.95)	0.287

* Analysis undertaken for 1050 infertile men with available data (726 MENA, 324 non-MENA).

Table 2 Detailed sperm analysis of infertile men: the MENA region compared to non-MENA (n = 13,892).

	MENA, n (%)	Non-MENA, n (%)	P
Concentration			<0.001
Azoospermia	530 (6.0)	311 (6.1)
Oligozoospermia	2331 (26.5)	900 (17.6)
Normal Concentration	5938 (67.5)	3882 (76.2)
Total motility			<0.001
Asthenozoospermia	2282 (27.6)	1116 (23.3)
Normal Motility	5987 (72.4)	3666 (76.7)
Morphology			0.001
Teratozoospermia	4382 (49.8)	2390 (46.9)
Normal Morphology	4417 (50.2)	2703 (53.1)
SDF ^*			0.26
Abnormal	316 (43.5)	117 (36.1)
Normal	410 (56.5)	207 (63.9)

* Analysis undertaken for 1050 infertile men with available data (726 MENA, 324 non-MENA).

Table 3 Number of infertile patients by year: the MENA and non-MENA regions.

Year	Infertile patients, n		Total, n
	MENA	Non-MENA
2012	1582	919	2501
2013	2333	1278	3611
2014	2307	1417	3724
2015	2577	1479	4056

Table 4 Semen analysis comparing MENA and non-MENA infertile patients by age.

	Age ≤ 40 years (n = 10 156)			Age > 40 years (n = 3736)
	MENA, n (%)	Non-MENA, n (%)	P	MENA, n (%)	Non-MENA, n (%)	P
Concentration	n = 6565	n = 3545	<0.001	n = 2234	n = 1548	<0.001
Azoospermia	371 (5.7)	207 (5.8)		159 (7.1)	104 (6.7)
Oligozoospermia	1720 (26.2)	619 (17.5)		611 (27.4)	281 (18.2)
Normal concentration	4474 (68.1)	2719 (76.7)		1464 (65.5)	1163 (75.1)
Motility	n = 6157	n = 3341	<0.001	n = 2112	n = 1441	0.04
Asthenozoospermia	1646 (26.7)	724 (21.7)		636 (30.1)	392 (27.2)
Normal motility	4511 (73.3)	2617 (79.3)		1476 (69.9)	1049 (72.8)
Morphology	n = 6612	n = 3544	<0.001	n = 2187	n = 1549	0.151
Teratozoospermia	3196 (48.3)	1578(44.5)		1186 (54.2)	812 (52.4)
Normal morphology	3416 (51.7)	1966 (55.5)		1001 (45.8)	737 (47.6)
SDF ( n = 1050)	n = 525	n = 222	0.14	n = 201	n = 102	0.46
Abnormal	215 (40.9)	67 (30.2)		101 (50.2)	50 (49)
Normal	310 (59.1)	155 (69.8)		100 (49.8)	52 (51)