Randomized controlled comparative trial between low dose dexmedetomidine sedation and that of fentanyl in children after surgical procedures in surgical Pediatric Intensive Care Unit

Peer review under responsibility of Egyptian Society of Anesthesiologists.

Figures & data

igure 1 CONSORT flowchart of the study.

able 1 Demographic data of the two groups.

	Fen group	Dex group
Age (years)	5.68 (±2.4)	6.12 (±2.9)
Sex (females/males)	14/11	13/12
Surgery duration (min)	103.3 (±18.6)	100.4 (±20.1)
Duration of sedation (h)	18	18
Rescue sedation (μg)	3.75 (±0.12)	3.64 (±0.14)

able 2 Descriptive analysis of the time for extubation between the two groups.

	Fen group	Dex group
Time for extubation (mini–max) in min	210–390	85–265
Median time for extubation (in min)	300	175
Mean time for extubation in min (SD)	341.4 (±125.4)	136.2 (±54.2)^⁎⁎

#x204E;⁎ Highly significant (P value <0.001).

able 3 Sedation scores in the ICU in postoperative period between the two groups [median (interquartile range)].

	Fen group					Dex group
Time (h)	1	4	10	18	24	1	4	10	18	24
Modified Ramsay Sedation Score	6(1)	5(2)	4(2)	4(2)	3(1)	6(1)	5(1)	5(2)	4(1)	3(1)
Tracheal suctioning score	5(2)	4(2)	4(1)	3(1)	2(1)	5(2)	4(1)	3(1)	3(1)	2(1)
Pediatric Intensive Care Unit score	4(1)	4(2)	3(1)	2(1)	2(1)	4(1)	4(1)	3(1)	3(1)	2(1)