Colloid versus crystalloid soaked gelfoam with morphine for postoperative pain relief after lumbar laminectomy

Peer review under responsibility of Egyptian Society of Anesthesiologists.

Figures & data

Table 3 The incidences for different complications.

Complications		Group A (n = 25)	Group B (n = 25)	Group C (n = 25)	P-value
PONV	Nausea only	8	4	4	0.28
		32.0%	16.0%	16.0%
	Vomiting	3	2	2	0.58
		12.0%	8.0%	8.0%
Itching	Mild	9	7	6	0.63
		36.0%	28.0%	24.0%
	Moderate	1	0	0	0.36
		4.0%	0%	0%
Urinary dysfunction	Urine retention	7	6	4	0.58
		28.0%	24.0%	16.0%

Data are expressed as number and percent (%). Chi-square was used for inter-group comparison. PONV: postoperative nausea and vomiting.

Table 1 Comparison of respiratory rate (RR) (breath/min).

Time	Group A (n = 25)	Group B (n = 25)	Group C (n = 25)	P-value
Baseline	13.20 ± 0.86	13.64 ± 1.43	13.60 ± 1.22	P1:0.20
	13(10–14)	14(10–18)	13(12–18)	P2:0.38
				P3:0.69
T 2 h	11.04 ± 0.78	11.56 ± 1.41	11.04 ± 0.88	P1:0.23
	11(10–13)^#	11(10–15)^#	11(10–14)^#	P2:0.85
				P3:0.19
T 4 h	10.96 ± 1.05	11.80 ± 1.22	11 ± 0.91	P1:0.01^⁎
	11(10–13)^#	12(10–14)^#	11(10–14)^#	P2:0.68
				P3:0.01^⁎
T 6 h	11.36 ± 1.22	12 ± 1.41	11.80 ± 1.41	P1:0.11
	11(10–14)^#	12(10–15)^#	11(10–15)^#	P2:0.30
				P3:0.52
T 10 h	13.68 ± 0.98	12.92 ± 1.18	11.92 ± 1.03	P1:0.01^⁎
	14(11–15)	13(11–15)^#	12(10–14)^#	P2:0.0001^⁎
				P3:0.004^⁎
T 14 h	14.80 ± 1.35	12.40 ± 1.44	12.40 ± 1	P1:0.0001^⁎
	15(13–17)^#	12(10–15)^#	12(11–14)^#	P2:0.0001^⁎
				P3:0.96
T 18 h	14.44 ± 1.50	12.80 ± 1.35	12.76 ± 1.61	P1:0.001^⁎
	14(12–17)^#	12(11–15)^#	13(11–19)^#	P2:0.0001^⁎
				P3:0.79
T 22 h	13.56 ± 1.22	13.08 ± 1.03	12.32 ± 0.94	P1:0.10
	13(11–17)	13(12–16)	12(10–14)^#	P2:0.0001^⁎
				P3:0.01^⁎
T 30 h	14.36 ± 1.60	13.40 ± 1.38	12.60 ± 0.81	P1:0.03^⁎
	14(11–18)^#	13(11–16)	12(11–14)^#	P2:0.0001^⁎
				P3:0.02^⁎
T 38 h	14.60 ± 1.29	13.84 ± 2.09	13.28 ± 1.36	P1:0.33
	15(12–17)^#	15(10–17)	13(11–16)	P2:0.002^⁎
				P3:0.21
T 48 h	14.36 ± 1.07	14.64 ± 1.46	14.72 ± 1.51	P1:0.73
	14(12–17)^#	14(12–18)^#	15(12–17)^#	P2:0.19
				P3:0.49

Data are expressed as mean ± standard deviation and median (minimum-maximum). P1: group A versus group B. P2: group A versus group C. P3: group B versus group C.

⁎ Significant inter-groups difference.

# Significant intra-group difference to baseline value.

Figure 1 Mean of VAS in the studied groups.

Table 2 Time to ambulation, time to first analgesic requirement, total postoperative analgesic consumption and time to discharge.

Variables	Group A (n = 25)	Group B (n = 25)	Group C (n = 25)	P-value
Time to ambulation (h)	6.88 ± 1.05	6.20 ± 1.29	6 ± 1.25	P1:0.12
	7(5–9)	6(4–10)	6(4–8)	P2:0.03^⁎
				P3:0.82
Time to first analgesic requirement (h)	11.88 ± 1.33	38.04 ± 2.05	43.04 ± 2.13	P1:0.0001^⁎
	12(10–15)	38(34–42)	43(39–46)	P2:0.0001^⁎
				P3:0.0001^⁎
Total postoperative analgesic consumption (mg) using diclofenac sodium amp. 75 mg	192 ± 48.7	57 ± 39.2	48 ± 36.7	P1:0.0001^⁎
	150(150–300)	75(0–150)	75(0–75)	P2:0.0001^⁎
				P3:0.40
Time to discharge (days)	2.20 ± 0.40	2.44 ± 0.76	2.24 ± 0.52	P1:0.32
	2(2–3)	2(2–4)	2(2–4)	P2:0.96
				P3:0.45

Data are expressed as mean ± standard deviation and median (minimum-maximum). P1: group A versus group B. P2: group A versus group C. P3: group B versus group C.

^#Significant intra-group difference to baseline value.

⁎ Significant inter-groups difference.