Automated control of end-tidal sevoflurane in living donor hepatectomy, a prospective, randomized, controlled study

Peer review under responsibility of Egyptian Society of Anesthesiologists.

Figures & data

Figure 1 Study flow chart.

Table 1 patient characteristics in the studied groups, data is presented as mean ± SD.

	MC group n = 20	EtC-2L group n = 20	EtC-0.5L group n = 20	P
Age (years)	29 ± 8	27 ± 8	30 ± 7	0.47
Weight (kg)	77 ± 2	78 ± 5	74 ± 9	0.09
Height (cm)	165 ± 10	167 ± 9	172 ± 11	0.155
BMI (kg/m^2)	27 ± 2	26 ± 3	25 ± 4	0.11
Basal HR (bpm)	81 ± 17	83 ± 21	87 ± 7	0.588
Basal MAP (mmHg)	88 ± 11	87 ± 21	89 ± 7	0.94
Anesthesia duration (min)	390 ± 85	399 ± 47	380 ± 55	0.7

BMI, body mass index, HR: heart rate, bpm: Beat per minute, MAP: Mean arterial pressure.

^* P value is considered significant if less than 0.05.

Table 2 Intraoperative monitoring (HR, MAP, BIS) among the two studied groups; MC group (n = 20), EtC-2L group (n = 20), EtC-0.5L group (n = 20). Data are presented as mean ± SD.

	HR (bpm)				MAP (mmHg)				BIS
	MC group n = 20	EtC-2L group n = 20	EtC-0.5L group n = 20	P	MC groupn = 20	EtC-2L group n = 20	EtC-0.5L group n = 20	P	MC groupn = 20	EtC-2L group n = 20	EtC-0.5L group n = 20	P
Induction	37 ± 14	78 ± 20	87 ± 5	0.046	89 ± 9	79 ± 18	85 ± 13	0.37	N/A	N/A	N/A	N/A
15 min	80 ± 15	84 ± 20	87 ± 5	0.39	86 ± 15	89 ± 14	83 ± 30	044	47 ± 3	54 ± 9	50 ± 4	0.48
30 min	83 ± 14	81 ± 17	87 ± 3	0.54	84 ± 11	86 ± 16	84 ± 6	0.41	48 ± 4	53 ± 9	51 ± 5	0.06
1st hour	79 ± 11	84 ± 15	87 ± 4	0.56	88 ± 6	86 ± 12	84 ± 8	0.06	51 ± 4	53 ± 10	50 ± 4	0.44
2nd hour	80 ± 8	88 ± 15	84 ± 11	0.21	83 ± 10	87 ± 7	86 ± 6	0.37	52 ± 5	53 ± 8	48 ± 2	0.02^*
3rd hour	81 ± 7	86 ± 13	85 ± 4	0.28	86 ± 5	89 ± 8	83 ± 5	0.36	53 ± 5	52 ± 7	49 ± 3	0.03
4th hour	84 ± 7	87 ± 10	88 ± 6	0.24	82 ± 4	89 ± 11	85 ± 3	0. 16	57 ± 7	52 ± 9	52 ± 1	0.12
5th hour	81 ± 9	87 ± 11	83 ± 6	0.37	87 ± 8	88 ± 6	87 ± 14	0. 16	53 ± 9	52 ± 9	51 ± 1	0.33
6th hour	88 ± 10	91 ± 12	89 ± 4	0.61	86 ± 7	84 ± 9	86 ± 4	0.655	51 ± 6	52 ± 7	49 ± 6	0.32

SD: standard deviation, HR; Heart rate, BPM: beat per minute, MAP, Mean arterial pressure, BIS; Bispectral index.

* P value is considered significant if less than 0.05.

Figure 2 Anesthetic gas consumption, button presses and extubation time for the 3 studied groups. P value is significant if less than 0.05. ^*Indicates significant difference between EtC-0.5L group and another group. ^#Indicates significant difference between EtC-2L group and another group.

Figure 3 Sevoflurane-related costs in the studied groups. P value is significant if less than 0.05. ^*Indicates significant difference between EtC-0.5L group and an another group. ^#Indicates significant difference between EtC-2L group and another group.