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Original Articles

Preventive and curative effects of Cocculus hirsutus (Linn.) Diels leaves extract on CCl4 provoked hepatic injury in rats

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Pages 264-269 | Received 08 Jun 2017, Accepted 13 Oct 2017, Published online: 08 Mar 2019

Figures & data

Table 1 Effects of ethanol extract from Cocculus hirsutus on serum GOT, GPT, ALP, LDH, and bilirubin levels in control and experimental rats against CCl4 induced toxicity.

Table 2 Effect of ethanol extract of Cocculus hirsutus on hepatic levels of TBARS, enzymatic and non-enzymatic antioxidants in control and experimental rats against CCl4 induced toxicity.

Fig. 1 Light microscopic photographs of liver histology in control and experimental rats. (A) Control mice showing normal histoarchitecture of hepatocytes, (B) A liver section of rat received CCl4 showing hepatocellular damage, (C) A liver section of rat received CCl4 + 250 mg/kg b·wt. EECH showing minimal damage to liver cells, and (D) A liver section of rat received CCl4 + 500 mg/kg b. wt. EECH showing almost normal architecture of liver. Hematoxilin and Eosin stain; Original magnification ×10.