Figures & data
Table A1 Some recent development in the field of lipid based emulsion for ocular delivery.
Table A2 Excipients used for the formulation of ocular lipid emulsion [Citation75].
Table A3 Patent granted on LEs for the ocular drug delivery.
M.A.MoustafaY.S.ElnaggarW.M.El-RefaieO.Y.AbdallahHyalugel-integrated liposomes as a novel ocular nanosized delivery system of fluconazole with promising prolonged effectInt J Pharm53420171424 N.Üstündağ-OkurE.H.GökçeD.İ.BozbıyıkS.EğrilmezÖ.ÖzerG.ErtanPreparation and in vitro–in vivo evaluation of ofloxacin loaded ophthalmic nano structured lipid carriers modified with chitosan oligosaccharide lactate for the treatment of bacterial keratitisEur J Pharm Sci632014204215 N.PatelH.NakraniM.RavalN.ShethDevelopment of loteprednol etabonate-loaded cationic nanoemulsified in-situ ophthalmic gel for sustained delivery and enhanced ocular bioavailabilityDrug Deliv23201637123723 S.K.BhartiK.KesavanPhase-transition W/O microemulsions for ocular delivery: evaluation of antibacterial activity in the treatment of bacterial keratitisOcul Immunol Inflamm252017463474 K.KesavanS.KantJ.K.PanditTherapeutic effectiveness in the treatment of experimental bacterial keratitis with ion-activated mucoadhesive hydrogelOcul Immunol Inflamm242016489492 N.GautamK.KesavanDevelopment of microemulsions for ocular deliveryTher Deliv82017313330 Kaswan R, inventor. University of Georgia Research Foundation Inc (UGARF), assignee.Ophthalmic treatment by topical administration of cyclosporin. United States patent US 4,649,047. 1987. Benita S, Elbaz E, inventors. Yissum Research Development Co of Hebrew University, assignee. Oil-in-water emulsions of positively charged particles. United States patent US 6,007,826. 1999. Simonnet JT, Sonneville O, Legret S, L'Oreal SA. Nanoemulsion based on oxyethylenated or non-oxyethylenatedsorbitan fatty esters, and its uses in the cosmetics, dermatological and/or ophthalmological fields. U.S. Patent 6,335,022. 2002. Benita S, Lambert G, inventors; Novagali SA. Yissum Research Development Co of Hebrew University, assignee. Method and composition for dry eye treatment. United States patent US 6,656,460. 2003. Carli F, Baronian M, Schmid R, Chiellini E, inventors. Azad Pharma Ag, assignee. Ophthalmic oil-in-water emulsions containing prostaglandins. United States patent US 8,414,904. 2013. Jain S, Kompella UB, Musunuri S, inventors. Ocugen Inc, University of Illinois, assignee. Methods and compositions for treating dry eye disease and other eye disorders. United States patent US 9,597,328. 2017.