Comparative clinical effectiveness of preoperative skin antiseptic preparations of chlorhexidine gluconate and povidone iodine for preventing surgical site infections in dogs

Peer review under responsibility of Faculty of Veterinary Medicine, Cairo University.

Figures & data

Fig. 1 Estimated marginal mean bacteria count before and after application of chlorhexidine gluconate + Cetrimide and povidone iodine respectively.

Table 1 Mean bacteria counts before and after application of chlorhexidine gluconate + Cetrimide and povidone-iodine respectively.

Disinfectant	Time period (min)	Mean	SE	95% CI
				From	To
Chlorhexdiine	Before	318,000	60988.159	189868.632	446131.368
	0	2431	457.551	1469.721	3392.279
	30	1695	336.495	988.049	2401.951
	60	1295	247.142	775.773	1814.227
	90	722	150.990	404.781	1039.219
Povidone-iodine	Before	348,000	60988.151	219868.632	476131.368
	0	2670	457.551	1708.721	3631.279
	30	2090	336.495	1383.049	2796.951
	60	1546	247.142	1026.773	2065.227
	90	981	150.990	663.781	1298.219

Table 2 Results of repeated measures ANOVA of disinfectant properties of chlorhexidine gluconate + Cetrimide and povidone-iodine over time using Bonferroni Multiple comparisons test.

Disinfectant	Time period (min)	Mean difference (cfu/mL)	P value
Chlorhexidine Gluconate + Cetrimide	Before – 0	315,569	0.001
	Before – 30	316,305	0.001
	Before – 60	316,705	0.001
	Before – 90	317,278	0.001
	0–30	736	0.002
	0–60	1136	0.036
	0–90	1709	0.005
	30–60	400	0.036
	30–90	973	0.005
	60–90	573	0.005
Povidone-Iodine	Before – 0	345,330	<0.001
	Before – 30	345,910	<0.001
	Before – 60	346,454	<0.001
	Before – 90	347,019	<0.001
	0–30	580	0.019
	0–60	1124	0.001
	0–90	1689	0.002
	30–60	544	0.002
	30–90	1109	0.001
	60–90	565	0.007