A sensitive and specific point-of-care detection assay for Zaire Ebola virus

Figures & data

Table 1 Performance of point-of-care test versus conventional real-time RT–PCR test for Ebola virus detection

	Point-of-care test
	Blood (n=429)	Swab (n=132)	All (n=561)
Prevalence (% of patients that tested positive by conventional real-time RT–PCR test)	286/429 (66.7%)	73/132 (55.3%)	359/561 (64.0%)
Sensitivity	284/286 (99.3%, 97.5%–99.9%)	71/73 (97.3%, 90.5%–99.7%)	355/359 (98.9%, 97.1%–99.7%)
Specificity	140/143 (97.9%, 94.0%–99.6%)	59/59 (100%, 93.9%–100%)	199/202 (98.5%, 95.7%–99.7%)
Negative predictive value	140/142 (98.6%, 95.0%–99.8%)	59/61 (96.7%, 88.7%–99.6%)	199/203 (98.0%, 95.0%–99.5%)
Positive predictive value	284/287 (99.0%, 97.0%–99.8%)	71/71 (100%, 94.9%–100%)	355/358 (99.2%, 97.6%–99.8%)

Abbreviations: confidence interval, CI; PCR with reverse transcription, RT–PCR.

Data are n/N (%) or n/N (%, 95% CI).