Figures & data
Figure 1 Protective effects of PEI against H1N1 and H3N2 challenge. (A) Body weight loss after 5LD50 H1N1 challenge. (B) Survival rate of mice in the PEI-pretreated group (n=10), CTB-pretreated group (n=7), and PBS-pretreated group (n=8) after 5 LD50 H1N1 challenge. (C) Lung virus titer on day 2 after 5 LD50 H1N1 challenge. For panels A to C, *a significant difference (*P<0.05) was observed between the PEI-pretreated group and the CTB- as well as PBS-pretreated groups. (D) Examination of lung pathology in lung tissue sections stained with hematoxylin and eosin. Original magnification: × 200. (E) Body weight loss of mice after 5 LD50 H3N2 challenge. (F) Survival rate of mice after 5 LD50 H3N2 challenge. For panels E and F, *a significant difference (*P<0.05) and **very significant difference (**P<0.01) were observed between the PEI- and PBS-pretreated groups. Data are expressed as means±SD. All results were repeated and verified at least twice.
