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Emerging Microbes & Infections Volume 7, 2018 - Issue 1
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Correspondence

Avian hepatitis E virus infection of duck, goose, and rabbit in northwest China

Baoyuan LiuDepartment of Preventive Veterinary Medicine, College of Veterinary MedicineNorthwest A&F University and Scientific Observing and Experimental Station of Veterinary Pharmacology and Diagnostic Technology, Ministry of Agriculture, China712100YanglingShaanxiChina
,
Mengnan FanDepartment of Preventive Veterinary Medicine, College of Veterinary MedicineNorthwest A&F University and Scientific Observing and Experimental Station of Veterinary Pharmacology and Diagnostic Technology, Ministry of Agriculture, China712100YanglingShaanxiChina
,
Beibei ZhangDepartment of Preventive Veterinary Medicine, College of Veterinary MedicineNorthwest A&F University and Scientific Observing and Experimental Station of Veterinary Pharmacology and Diagnostic Technology, Ministry of Agriculture, China712100YanglingShaanxiChina
,
Yiyang ChenDepartment of Preventive Veterinary Medicine, College of Veterinary MedicineNorthwest A&F University and Scientific Observing and Experimental Station of Veterinary Pharmacology and Diagnostic Technology, Ministry of Agriculture, China712100YanglingShaanxiChina
,
Yani SunDepartment of Preventive Veterinary Medicine, College of Veterinary MedicineNorthwest A&F University and Scientific Observing and Experimental Station of Veterinary Pharmacology and Diagnostic Technology, Ministry of Agriculture, China712100YanglingShaanxiChina
,
Taofeng DuDepartment of Preventive Veterinary Medicine, College of Veterinary MedicineNorthwest A&F University and Scientific Observing and Experimental Station of Veterinary Pharmacology and Diagnostic Technology, Ministry of Agriculture, China712100YanglingShaanxiChina
,
Yuchen NanDepartment of Preventive Veterinary Medicine, College of Veterinary MedicineNorthwest A&F University and Scientific Observing and Experimental Station of Veterinary Pharmacology and Diagnostic Technology, Ministry of Agriculture, China712100YanglingShaanxiChina
,
En-Min ZhouDepartment of Preventive Veterinary Medicine, College of Veterinary MedicineNorthwest A&F University and Scientific Observing and Experimental Station of Veterinary Pharmacology and Diagnostic Technology, Ministry of Agriculture, China712100YanglingShaanxiChinaCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0001-8942-013X
ORCID Icon &
Qin ZhaoDepartment of Preventive Veterinary Medicine, College of Veterinary MedicineNorthwest A&F University and Scientific Observing and Experimental Station of Veterinary Pharmacology and Diagnostic Technology, Ministry of Agriculture, China712100YanglingShaanxiChinaCorrespondence[email protected]
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Pages 1-3 | Received 02 Jan 2018, Accepted 25 Mar 2018, Published online: 02 May 2018

Figures & data

Fig. 1 Avian HEV gene analysis and clinical evaluation of the virus infected rabbits

a Phylogenetic trees based on the sequences of four partial of HEV ORF2 genes (CHN-SN-C2, CHN-SN-D2, CHN-SN-G2, and CHN-SN-R2) isolated in this study and other HEVs from various animal species. The trees were generated by the neighbor-joining method with bootstrap tests of 1000 replicates using the MEGA 7.0 software. b Viremia/fecal viral shedding, ALT levels, and antibody levels in rabbits experimentally infected with CaHEV. c Microscopic lesions in livers from negative control rabbits (left) and rabbits experimentally infected with CaHEV (right) showed lymphocytic venous periphlebitis (arrows). Liver sections were stained with hematoxylin and eosin

Fig. 1 Avian HEV gene analysis and clinical evaluation of the virus infected rabbitsa Phylogenetic trees based on the sequences of four partial of HEV ORF2 genes (CHN-SN-C2, CHN-SN-D2, CHN-SN-G2, and CHN-SN-R2) isolated in this study and other HEVs from various animal species. The trees were generated by the neighbor-joining method with bootstrap tests of 1000 replicates using the MEGA 7.0 software. b Viremia/fecal viral shedding, ALT levels, and antibody levels in rabbits experimentally infected with CaHEV. c Microscopic lesions in livers from negative control rabbits (left) and rabbits experimentally infected with CaHEV (right) showed lymphocytic venous periphlebitis (arrows). Liver sections were stained with hematoxylin and eosin
Supplemental material

Supplemental Table S1

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Supplemental Table S2

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Supplemental Figure S1

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Distribution of percent inhibition (PI) of sera from chickens, ducks, geese, and rabbits in the mixed group using a blocking ELISA. The dotted lines represent the cut-off values of the blocking ELISA

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