A novel human coronavirus OC43 genotype detected in mainland China

Figures & data

Fig. 1 Genetic analysis of the HCoV-OC43 strains based on the whole-genome sequences.

a Phylogenetic tree of the HCoV-OC43 strains based on whole-genome sequences. The tree was constructed by using the maximum likelihood (ML) method with the best-fit general time reversible model with gamma-distributed rate variation across sites and 1000 bootstrap replicates implemented in MEGA 5.03. Bootstrap values over 70% are shown in the nodes. b Estimation of pairwise genetic distances between genotype H and genotypes A–G of HCoV-OC43 strains based on the whole-genome sequences

Demographic and clinical manifestation of HCoV-OC43 positive cases

Genotype	Strains ID	Collection date	Age (year)	Gender	Clinical manifestation
G	BJ-124/15	2015/5/6	0.08	Male	Cough, Sneezing, nasal discharge
	WZ-303/15	2015/5/6	1.58	Male	Fever, cough, expectoration
	WZ-522/15	2015/5/16	6.58	Male	Cough, nasal discharge
	GZYF-26/15	2015/5/18	3.83	Male	Fever, cough, nasal discharge, headache, sore throat
	BJ-165/15	2015/6/9	0.42	Male	Fever, cough, expectoration
	BJ-221/15	2015/8/14	1.17	Male	Fever, expectoration
	YC-207/16	2016/5/5	2.75	Male	Fever, expectoration
	ZJ-459/16^a	2016/6/20	9.25	Female	Fever, pectoralgia, pleural effussion
H	YC-55/15	2015/3/12	3.25	Female	Fever, cough, expectoration
	BJ-112/15	2015/4/22	0.17	Female	Fever, expectoration
	BJ-164/15	2015/6/2	0.5	Female	Cough, sore throat, hoarseness of voice
	YC-67/15	2015/6/4	0.83	Female	Fever, cough
	YC-68/15	2015/6/5	0.42	Male	Fever, expectoration
	YC-72/15	2015/6/13	4.92	Male	Fever
	CC-23/15	2015/7/13	2.33	Female	Fever, expectoration

Severe pneumonia case was indicated by symbol “a”