Comparison of thromboelastometry by ROTEM^® Delta and ROTEM^® Sigma in women with postpartum haemorrhage

Figures & data

Figure 1. Graphical display of coagulation as provided by ROTEM^® devices.

Table 1. Characteristics of the women included.

Patients	n = 23
Maternal characteristics
Age (years)	35 (31–38)^a
BMI (kg/m^2)	23 (21–28)
Ethnicity, Caucasian	17 (74%)
Gestational age in weeks	39.0 (37.4–39.3)
Mode of birth
Caesarean section	10 (43)^b
Vaginal	13 (57)
Primary cause of bleeding
Uterine atony	7 (30)
Retained placenta	8 (35)
Surgical bleeding	6 (26)
Genital tract trauma	1 (4)
Placental abruption	1 (4)
Pathological ingrowth of placenta/placenta previa/ uterine rupture/coagulopathy	–
Bleeding characteristics
Total volume blood loss in mL	1400 (1200–1800)

^aValues are median (interquartile range).

^bRepresented in percentage.

Figure 2. Scatterplots and Spearman’s correlation coefficients (r_s) for EXTEM, INTEM, FIBTEM and APTEM parameters measured on ROTEM^® Delta and Sigma devices.

Table 2. Differences between ROTEM^® Delta and Sigma for CT, A5, A10, A20 and MCF.^a

	EXTEM			INTEM			FIBTEM			APTEM
	Δ	IQR	p Value^b	Δ	IQR	p Value^b	Δ	IQR	p Value^b	Δ	IQR	p Value^b
CT s	−6.5	−9.25 to −1.75	<.01	3.5	−2 to 7	.01	−6	−10 to −1	<.01	− 4	−7 to 4.5	.17
A5 mm	−1.5	−3.25 to 2.0	.16	2	1 to 3	<.01	−4	−5 to −2	<.01	0	−1 to 3	.17
A10 mm	0.5	−1.0 to 1.25	.32	2	1 to 3	<.01	−3	−3 to −1	.01	2	1 to 4	<.01
A 20 mm	0.0	−1.25 to 1.25	.77	1	0 to 2	<.01	−2	−3 to −1	.07	2	0.5 to 2.5	.02
MCF mm	−0.5	−2.25 to 1.0	.18	1	0 to 1	<.01	−1	−2 to 0	.12	0	−1 to 2	.52

Δ: difference; IQR: interquartile range; CT: clotting time; MCF: maximum clot firmness.

^aValues are median (interquartile range).

^bp Values of Wilcoxon signed-rank test.

Table 3. Correlation between ROTEM^® Delta and Sigma for CT, A5, A10, A20 and MCF.

	EXTEM			INTEM			FIBTEM			APTEM
	n	rs	p Value^a	n	rs	p Value^a	n	rs	p Value^a	n	rs	p Value^a
CT s	26	0.180	.38	26	0.855	<.01	23	0.416	.05	25	−0.87	.68
A5 mm	26	0.904	<.01	26	0.950	<.01	23	0.712	<.01	25	0.850	<.01
A10 mm	26	0.905	<.01	26	0.910	<.01	23	0.738	<.01	25	0.805	<.01
A 20 mm	26	0.885	<.01	26	0.907	<.01	23	0.733	<.01	25	0.759	<.01
MCF mm	26	0.840	<.01	26	0.940	<.01	23	0.769	<.01	25	0.736	<.01

r_s: Spearman’s correlation coefficient; CT: clotting time; MCF: maximum clot firmness.

^aCorrelation coefficients and p-value by Spearman’s rank test.