Geographical variations in the incidence of oesophageal cancer in Sweden

Figures & data

Table 1. Classification of geographical regions in Sweden.

NUTS national area	County	Healthcare regions
Stockholm	Stockholm	Stockholm
East Middle Sweden	Uppsala	Uppsala-Örebro
	Södermanland	Uppsala-Örebro
	Östergötland	Southeast
	Örebro	Uppsala-Örebro
	Västmanland	Uppsala-Örebro
South Sweden	Blekinge	South
	Skåne	South
North Middle Sweden	Värmland	Uppsala-Örebro
	Dalarna	Uppsala-Örebro
	Gävleborg	Uppsala-Örebro
Middle Norrland	Västernorrland	North
	Jämtland	North
Upper Norrland	Västerbotten	North
	Norrbotten	North
Småland and the islands	Jönköping	Southeast
	Kronoberg	South
	Kalmar	Southeast
	Gotland	Stockholm
West Sweden	Halland	West and South
	Västra Götaland	West

NUTS: Nomenclature of Territorial Units for Statistics.

Figure 1. Age-standardised incidence rate of oesophageal cancer by sex and histological type for each national area in Sweden in 1972–2016. (a) adenocarcinoma in men; (b) adenocarcinoma in women; (c) squamous cell carcinoma in men; (d) squamous cell carcinoma in women.

Figure 2. County-specific age-standardised incidence rate (per 100,000 person-years) of (a) oesophageal adenocarcinoma and (b) oesophageal squamous cell carcinoma in men in Sweden in 2002–2016. The stars indicate the locations of the specialised upper gastrointestinal oncology units.

Table 2. Crude and age-standardised incidence rates of oesophageal adenocarcinoma by sex and calendar period for each county in Sweden, 1/100,000 person-years.

County	Men									Women
	1972–1986			1987–2001			2002–2016			1972–1986			1987–2001			2002–2016
	N	CR	ASR	N	CR	ASR	N	CR	ASR	N	CR	ASR	N	CR	ASR	N	CR	ASR
Stockholm	119	1.1	1.4	273	2.2	2.9	474	3.1	4	34	0.3	0.3	49	0.4	0.4	107	0.7	0.7
Uppsala	22	1.2	1.8	25	1.2	1.6	94	3.8	4.4	7	0.4	0.5	8	0.4	0.4	21	0.8	0.8
Södermanland	17	0.9	1.1	42	2.2	2.5	112	5.6	5.2	5	0.3	0.3	11	0.6	0.5	17	0.8	0.7
Östergötland	21	0.7	0.9	28	0.9	1.0	134	4.2	4.3	5	0.2	0.2	10	0.3	0.3	31	1.0	0.9
Jönköping	27	1.1	1.4	25	1.0	1.1	113	4.5	4.4	6	0.3	0.3	7	0.3	0.3	30	1.2	1.0
Kronoberg	6	0.5	0.4	21	1.6	1.7	66	4.8	4.5	2	0.2	0.1	2	0.2	0.1	11	0.8	0.7
Kalmar	13	0.7	0.7	23	1.3	1.3	89	5.1	4.5	3	0.2	0.2	10	0.6	0.4	16	0.9	0.7
Gotland	10	2.4	2.8	7	1.6	1.8	29	6.8	6.2	2	0.5	0.4	2	0.5	0.4	1	0.2	0.2
Blekinge	4	0.3	0.3	19	1.7	1.7	71	6.1	5.7	3	0.3	0.3	10	0.9	0.8	15	1.3	1.0
Skåne	59	0.8	1.0	168	2.1	2.3	399	4.4	4.5	10	0.1	0.1	53	0.6	0.6	79	0.8	0.8
Halland	13	0.8	1.0	34	1.7	2.0	78	3.5	3.5	11	0.6	0.7	1	0.1	<0.1	12	0.5	0.5
Västra Götaland	83	0.8	1.0	153	1.4	1.6	402	3.4	3.6	22	0.2	0.2	40	0.4	0.3	87	0.7	0.6
Värmland	26	1.2	1.3	58	2.8	2.8	111	5.4	4.9	1	<0.1	<0.1	14	0.7	0.6	21	1.0	0.7
Örebro	21	1.0	1.1	55	2.7	2.9	104	5.0	4.9	4	0.2	0.2	12	0.6	0.5	17	0.8	0.7
Västmanland	16	0.8	1.0	40	2.1	2.5	63	3.3	3.2	1	0.1	0.1	9	0.5	0.4	18	0.9	0.8
Dalarna	22	1.0	1.1	71	3.3	3.5	119	5.7	5.1	2	0.1	0.1	9	0.4	0.3	27	1.3	1.0
Gävleborg	22	1.0	1.2	39	1.8	1.9	120	5.8	5.3	5	0.2	0.3	18	0.8	0.7	36	1.7	1.3
Västernorrland	10	0.5	0.6	9	0.5	0.4	93	5.1	4.6	2	0.1	0.1	8	0.4	0.3	23	1.3	1.0
Jämtland	12	1.2	1.4	17	1.7	1.6	27	2.8	2.7	1	0.1	0.1	2	0.2	0.2	6	0.6	0.5
Västerbotten	4	0.2	0.3	14	0.7	0.8	61	3.1	3.2	1	0.1	0.1	7	0.4	0.4	23	1.2	1.0
Norrbotten	10	0.5	0.6	11	0.6	0.6	85	4.5	4.1	4	0.2	0.3	3	0.2	0.1	19	1.0	0.8

N: number of new cases; CR: crude rate; ASR: age-standardised rate.

Table 3. Crude and age-standardised incidence rates of oesophageal squamous cell carcinoma by sex and calendar period for each county in Sweden, 1/100,000 person-years.

County	Men									Women
	1972–1986			1987–2001			2002–2016			1972–1986			1987–2001			2002–2016
	N	CR	ASR	N	CR	ASR	N	CR	ASR	N	CR	ASR	N	CR	ASR	N	CR	ASR
Stockholm	601	5.4	7.4	475	3.8	4.9	406	2.7	3.3	210	1.8	1.9	271	2.1	2.1	214	1.4	1.4
Uppsala	59	3.3	4.8	51	2.5	3.3	40	1.6	1.8	30	1.6	1.9	19	0.9	1.0	27	1.1	1.1
Södermanland	39	2.1	2.5	54	2.8	3.0	57	2.8	2.6	24	1.3	1.3	34	1.8	1.6	26	1.3	1.1
Östergötland	75	2.6	3.0	73	2.4	2.7	56	1.7	1.8	23	0.8	0.7	46	1.5	1.4	29	0.9	0.8
Jönköping	63	2.7	3.2	72	3.0	3.2	54	2.1	2.2	28	1.2	1.2	38	1.5	1.3	34	1.3	1.1
Kronoberg	33	2.5	2.8	40	3.0	3.2	40	2.9	2.8	19	1.5	1.4	18	1.4	1.2	24	1.8	1.5
Kalmar	38	2.1	2.1	51	2.9	3.0	42	2.4	2.0	17	0.9	1.0	23	1.3	1.1	21	1.2	0.9
Gotland	16	3.9	4.0	16	3.8	4.1	8	1.9	1.7	2	0.5	0.4	6	1.4	1.3	7	1.6	1.3
Blekinge	35	3.0	3.4	55	4.9	4.8	30	2.6	2.5	23	2.0	2.0	27	2.4	2.0	18	1.6	1.2
Skåne	405	5.4	6.2	381	4.7	5.3	270	3.0	3.0	139	1.8	1.8	198	2.4	2.1	181	1.9	1.7
Halland	67	3.9	4.3	85	4.3	4.7	55	2.5	2.4	23	1.4	1.4	20	1.0	0.9	32	1.4	1.2
Västra Götaland	356	3.4	4.0	350	3.2	3.6	272	2.3	2.4	150	1.4	1.5	194	1.7	1.6	181	1.5	1.4
Värmland	40	1.9	1.9	58	2.8	2.6	36	1.8	1.6	22	1.0	1.0	30	1.4	1.2	28	1.4	1.0
Örebro	59	2.9	3.6	53	2.6	2.7	40	1.9	1.8	23	1.1	1.1	32	1.5	1.3	29	1.4	1.1
Västmanland	45	2.3	2.6	47	2.4	2.8	47	2.4	2.2	23	1.2	1.5	33	1.7	1.6	26	1.3	1.1
Dalarna	48	2.3	2.7	50	2.3	2.5	38	1.8	1.6	37	1.7	1.6	31	1.4	1.2	25	1.2	0.9
Gävleborg	73	3.3	3.6	70	3.3	3.5	55	2.6	2.3	47	2.1	2.0	44	2.0	1.6	27	1.3	1.0
Västernorrland	79	4.0	4.4	85	4.4	4.4	39	2.1	2.0	48	2.4	2.2	39	2.0	1.6	28	1.5	1.2
Jämtland	25	2.5	2.7	33	3.3	3.3	17	1.8	1.6	15	1.5	1.3	20	2.0	1.7	8	0.8	0.7
Västerbotten	48	2.6	3.3	49	2.6	2.9	41	2.1	2.1	26	1.4	1.6	25	1.3	1.3	25	1.3	1.2
Norrbotten	51	2.5	3.9	58	2.9	3.4	53	2.8	2.7	35	1.8	2.3	39	2.0	1.9	31	1.7	1.3

N: number of new cases; CR: crude rate; ASR: age-standardised rate.

Figure 3. Distribution of oesophageal cancer patients diagnosed at different tumour stages (a) by national area and (b) by healthcare region in Sweden in 2004–2016.