Cohort profile and heritability assessment of familial pancreatic cancer: a nation-wide study

Figures & data

Figure 1. Histogram for the distribution of pedigree size (a), sibship size (b) and parent-offspring relatedness (c,d).

Figure 2. Histogram for median age at PDAC diagnosis (a) and median age at death (b). Kaplan–Meier plot for age at death (c) and survival time from diagnosis to death (d), for male (blue) and female (red) PDAC patients.

Table 1. Comparison of FDRs between PDAC and unaffected groups.

	PDAC			Unaffected
	Male	Female	Total	Male	Female	Total	p Value
All	38 (46%)	45 (54%)	83	195 (54%)	164 (46%)	359	.17
Siblings	33 (46%)	39 (54%)	72	96 (55%)	79 (45%)	175	.21
Parent-offspring	38 (46%)	44 (54%)	82	131 (56%)	104 (44%)	235	.14

Table 2. Age at diagnosis and age at death of PDAC patients.

Variables	Males	Females	All	p Value
Age at diagnosis, median (mean), years	60 (60)	68 (65)	66 (63)	.08
Age at diagnosis, range, years	34–96	38–87	34–96	–
Age at death, median (mean), years	62 (61)	69 (67)	67 (64)	.28
Age at death, range, years	35–96	40–87	35–96	–
Time from diagnosis to death, median, months	8.5	6.7	7.6	.66
Time from diagnosis to death, range, months	0–123.2	0–71.6	0–123.2	–