Endoscopic full-thickness resection of benign and malignant colon lesions with one-year follow up in a Danish cohort

Figures & data

Figure 1. Flowchart of patient selection and study outcomes.

Table 1. Patient and lesion characteristics.

Sex, n (%)
Female	13 (50)
Male	13 (50)
Age, median (range)	70 (57–81)
ASA score, n (%)
ASA I	0
ASA II	15 (58)
ASA III	11 (42)
ASA IV	0
Comorbidities, n (%)
Presence of at least 1 comorbidity	17 (65)
Hypertension	9 (35)
Diabetes mellitus	4 (15)
Cardiovascular comorbidities	6 (23)
Chronic obstructive pulmonary disease	5 (19)
Other^a	2 (8)
Use of anticoagulants, n (%)
Warfarin	2 (8)
Direct oral anticoagulants	4 (15)
Anti-platelets	3 (12)
Indication for EFTR, n (%)
Untreated lesions	6 (23)
Incomplete resection	17 (65)
Late recurrence	3 (12)
Location of lesion, n (%)
Coecum	3 (12)
Ascending colon	6 (23)
Transverse colon	4 (15)
Descending colon	6 (23)
Sigmoid colon	6 (23)
Rectosigmoid transition	1 (4)

^aOther refers to cirrhosis and chronic pancreatitis.

EFTR: Endoscopic full thickness resection; ASA: American Society of Anesthesiologists.

Table 2. Procedural data.

Lesions reached with FTRD, n (%)	23 (89)
Technical success, n (%)	21 (81)
Duration of procedure in min, median (range)
Total procedure	69 (30–162)
Reaching and marking the lesion	15 (5–35)
Mounting the FTRD on the endoscope	8 (4–24)
Reaching, deploying and retracting	21 (10–93)
Medications, n (%)
Conscious sedation	11 (42)
NAPS	3 (12)
General anaesthesia	12 (46)

FTRD: full-thickness resection device; NAPS: nurse-administered propofol sedation.

Table 3. Data on resected specimens.

Size, maximum diameter in mm, mean (range)	23 (10–35)
Full thickness, n (%)	18 (86)
R0 resection	18 (86)
Histology, n (%)
Adenoma with low-grade neoplasia	6 (27)
Adenoma with high-grade neoplasia	1 (5)
Adenocarcinoma*	5 (23)
Granulation tissue	6 (27)
Normal tissue	4 (18)

*They were all Kikuchi sm3.

Data availability statement

The data that support the findings of this study are available from the corresponding author, MB, upon reasonable request.