Abstract
Treatment of DMSO/water solutions of β‐bromo‐α‐(ethylsulfanyl)cinnamonitriles with sodium sulphide and α‐halo acetic acids derivatives followed by cyclization in a potassium carbonate/acetone/DMSO mixture gave the expected 3‐amino‐5‐aryl‐4‐(ethylsulfanyl)thiophene‐2‐carboxylic acids derivatives in fair yields.
Acknowledgments
The authors are grateful to F. Mongin for many helpful discussions and to P. Guenot for recording mass spectra.