Efficient and Green Method for the Synthesis of 1,5‐Benzodiazepine and Quinoxaline Derivatives in Water

Abstract

Various 1,5‐benzodiazepine and quinoxaline derivatives have been synthesized in water with excellent yields using a catalytic amount of indium chloride at room temperature. This synthetic protocol is nontoxic, safe, and environmentally benign.

Keywords:

• 1,5‐benzodiazepine
• indium chloride
• Lewis acid
• quinoxaline
• water media

Acknowledgment

The authors acknowledge the director, P. G. Rao, and N. Borthakur, Head of Division (HOD), Synthetic Organic Chemistry Division, the Analytical Division of Regional Research Laboratory (RRL), Jorhat, Assam, India, for their help. Also, P. G. and P. H. are grateful to the Council of Scientific and Industrial Research (CSIR) for its grant of junior research fellowships.