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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 38, 2008 - Issue 2
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Original Articles

Additive‐Free Thiolysis of Epoxides in Water: A Green and Efficient Regioselective Pathway to β‐Hydroxy Sulfides

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Pages 282-289 | Received 10 Jan 2007, Published online: 18 Jan 2008
 

Abstract

Room‐temperature ring opening of various epoxides with aromatic thiols was carried out in water in the absence of any Lewis acid or additive. High yields of β‐hydroxy sulfides with excellent regioselectivity were obtained under very environmentally friendly conditions.

Acknowledgment

The Ministry of Science, Research, and Technology of Iran is gratefully acknowledged for partial financial support of this work.

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