Synthesis of a New Ditopic Ligand Possessing Linear and Cyclic Tetraaza Subunits

Abstract

An easy‐to‐run route to a new ditopic ligand possessing linear and cyclic tetraaza subunits is described. In the first step, the reaction consists in the preparation of a triprotected cyclam bearing a 3‐bromopropyl pendant side chain. A subsequent reaction with a bisaminal protected linear tetraamine gives, after deprotection, the desired ditopic ligand.

Keywords:

• Bisaminal
• cyclam
• ditopic ligand
• linear tetraamine
• phosphoryl group