Abstract
A simple synthesis of novel (Z)-3-arylidene-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-ones from bromo compounds derived from Baylis–Hillman adducts involving selective S-alkylation followed by a lactum formation has been described.
ACKNOWLEDGMENTS
We thank Department of Science & Technology (New Delhi) for the financial support under the fast track scheme. We thank Department of Science & Technology-Fund for Improvement of Science & Technology Infrastructure in Higher Educational Institutions for the funding program at the Department of Organic Chemistry, University of Madras, Chennai.
Notes
a All the products gave satisfactory IR, 1H NMR (300 MHz), 13C NMR (75 MHz), and mass spectral data and elemental analyses.
b Yields of the pure product (6a–k) obtained after column chromatography.