Abstract
The air-stable and easy to prepare nonsymmetric Schiff base ligands have been synthesized and proven to be efficient ligands for Suzuki cross-coupling reaction between aryl bromides and arylboronic acids using PdCl2(CH3CN)2 as palladium source under aerobic conditions. The coupling reaction proceeded smoothly using N-[(3,4-dimethoxyphenyl)methylene]-1,2-benzenediamine (L3) as ligand under mild conditions to provide 4-substituted styrene compounds in good yields.
Notes
a Reaction conditions: p-bromostyrene (0.50 mmol), phenylboronic acids (0.75 mmol), PdCl2(CH3CN)2 (0.5% mmol), base (1.5 mmol), solution (2.0 mL), temperature 80°C, reaction time 10 h.
b Isolated yield.
a Reaction conditions: aryl bromides (0.50 mmol), arylboronic acids (0.75 mmol), L3 (0.75 mmol%), PdCl2 (CH3CN)2 (0.50 mmol%), base (1.50 mmol), toluene (2.0 mL), 80°C, reaction time 10 h.
b Isolated yield.