Abstract
The synthesis of 1,4-diisocyanato-4-methylpentane was accomplished starting from isobutyronitrile in six steps with 53% overall yield. The two isocyanates were installed by a double Curtius rearrangement. The product reacts with alcohol in a regioselective manner.
ACKNOWLEDGMENTS
The generous financial support from the Army Research Laboratory is gratefully acknowledged. Thanks to Ann M. Moorehead of the Technical Library for obtaining Ref. 1.
Notes
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