Abstract
The reaction of pyrrole/furan aldehyde with Grignard reagent and pyrrole/N-methyl pyrrole in sequence allows efficient synthesis of a number of meso-elaborated bis(heterocyclyl)methanes, which are otherwise difficult to obtain through a direct aldehyde condensation route.
ACKNOWLEDGMENT
This work was supported by financial assistance from the Department of Science and Technology (SR/S1/OC-27/2009).
Notes
a Isolated yield.
b Yields in parentheses refer to the use of 2.0 equiv of 3.