Three-Component, One-Pot Synthesis of Benzo[b][1,4]oxazines in Ionic Liquid 1-Butyl-3-methylimidazolium Bromide

Abstract

Benzo[b][1,4]oxazines have been synthesized in good to excellent yields in the presence of the ionic liquid 1-butyl-3-methylimidazolium bromide [bmim]Br under relatively mild conditions without any added catalyst, The method offers the advantages of good yields and short reaction times, and the ionic liquid can be easily separated from the product and reused.

GRAPHICAL ABSTRACT

Keywords:

• Benzo[b][1,4]oxazines
• [bmim]Br
• ionic liquid
• isocyanide
• multicomponent reactions

ACKNOWLEDGMENT

We gratefully acknowledge financial support from the Research Council of Razi University.

Notes

^a Known compound.

^b New compound.