Abstract
A rapid and efficient ultrasound-promoted protocol for iodination of aromatic and heteroaromatic compounds, using molecular iodine in the presence of aqueous hydrogen peroxide in water without any cosolvent, has produced versatile iodinated organic molecules with potential application in organic synthesis and medicine in short reaction times and good to excellent yields.
GRAPHICAL ABSTRACT
Notes
a Reaction conditions: 2 mmol of compound 1, the indicated amount of I2, the indicated amount of H2O2 (30%), and 10 mL of H2O were maintained under sonication (20 KHz, 100 W) for the period of time presented.
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