Abstract
2-Amino-4-(2-hydroxynaphthyl)-4H-chromene-3-carbonitriles were synthesized by Michael addition of various 3-cyanoiminocoumarins and β-naphthol in good yield. The heterocyclization of these materials in an acidic medium leads new heterocyclic compounds, which have not previously been described, in moderate to good yields and good selectivity. The synthesized compounds were characterized by infrared, 1H NMR, 13C NMR, two-dimensional NMR, and elemental analysis.
GRAPHICAL ABSTRACT
Notes
a Isolated yield.
a Isolated yield.